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Chromosome alterations in two cases of thyroid papillary adenocarcinoma

Mário Sérgio Mantovani^I; Maria Isabel Ziembar^I; José Barbieri Neto^II; Cacilda Casartelli^I

^IDepartamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (USP), Av. Bandeirantes 3900, 14049-900 Ribeirao Preto, SP, Brasil. Send correspondence to C.C.
^IIDepartamento de Patologia, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brasil

ABSTRACT

Papillary carcinomas are the most frequent thyroid tumors. We report a cytogenetic study of two cases of epithelial thyroid carcinoma of the papillary type using GTG banding techniques. The modal number was 46 chromosomes in both cases. No structural alteration was detected. Numerical alterations were present in a random manner, probably due to the instability of the neoplastic tissue.

Keywords: Chromosome alterations; thyroid papillary; adenocarcinoma.

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