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Cytogenetic investigation of four low grade gliomas

Maria Isabel Ziembar; Cacilda Casartelli

Departamento Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo,14049-900 Ribeirão Preto, SP, Brasil. Send correspondence to C.C.

ABSTRACT

Four low-grade gliomas - two oligodendrogliomas and two astrocytomas - were analyzed cytogenetically. All cases exhibited monosomies of chromosomes 10 and 11. The astrocytomas shared monosomies of chromosomes 8, 9, 10, 11, 12, 18 and 20. Losses of chromosomes 3, 5, 6,10 and 11 were present in both oligodendrogliomas, and except for monosomy of chromosome 6, were also identified in the pilocytic astrocytoma.

Keywords: cytogenetic; investigation; grade gliomas.

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