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Studies on polymorphism segregation in northeastern Brazil. II. Pairs of relatives

Maria Manuela da Fonseca Moura^I; H. Krieger^II

^IDepartamento de Genética, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, 21045-900 Rio de Janeiro, RJ, Brasil
^IIDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05508-900 São Paulo, SP, Brasil. Send correspondence to H.K.

ABSTRACT

Two relatively large Northeastern Brazilian samples were analysed in order to study the intrafamilial behavior of several polymorphisms, through pairs of relatives and sex distributions. Except for samples which include more than one paired observation per family, no excess of significant departure from theoretical expectation was found. The excess verified both in mother x offspring and in sib pairs, when the entire offspring were included in the sample, testify to the sensitivity of the method to detect violations of the independence criterion. No associations with sex were detected for any of the polymorphic systems studied in both samples.

Keywords: polymorphism segregation; northeastern Brazil; pairs of relatives.

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