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The OAV-Spectrum and associated anomalies in 77 patients

Jenny J. van den Ende; Yolande van Bever; Antonio Richieri-Costa

Serviço de Genética Clínica, Hospital de Pesquisa e Reabilitação de Lesões Lábio-Palatais, Universidade de São Paulo, Caixa Postal 620, 17043 Bauru, SP, Brasil. Send correspondence to A.R.C.

ABSTRACT

We have studied 77 patients belonging to the OAV-spectrum. These patients were grouped into four different categories according to their clinical signs: Goldenhar syndrome, oculoauriculovertebral dysplasia, typical hemifacial microsomia, and those only with pre-auricular tags, in order to compare the frequency of associated anomalies and recurrence rates. We have listed and compared our clinical findings with those found in the literature. There are few associated anomalies in the last group (pre-auricular tags) when compared with the other three groups, indicating that pre-auricular tags could represent a distinct anomaly.

Keywords: OAV-Spectrum; anomalies; patients.

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