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Stabilization of a duplicated segment Dp (H-I) in an uvs mutant of Aspergillus nidulans through genetic mechanisms

Marialba A.A. de Castro Prado^I; Tânia M.A. Domingues Zucchi^II

^IDepartamento de Biologia, Fundação Universidade Estadual de Maringá, Av. Colombo, 3690, 87015 Maringá, PR, Brasil
^IIDepartamento de Parasitologia, Instituto de Ciências Biomédicas (II), Cidade Universitária, Caixa Postal 4365, 05508 São Paulo, SP. Send correspondence to T.MA.D.Z.

ABSTRACT

This research presents an analysis of a mutant with a duplicated segment of chromosome II translocated to the paba-y interval of chromosome I. This insertion promotes alterations in the meiotic and mitotic behavior of the strain, mitotic instability, uvs character and deteriorated morphology. The uvs character is closely linked to the insertion point and was shown to be responsible for the mitotic instability. The removal of this mutation through recombination promotes the stabilization of the strain.

Keywords: UVS mutant; Aspergillus nidulans.

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