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Similarity coefficient of jaccard applied to studies on gene regulation

Marion Schiengold; Helga Winge

Departamento de Genética, Universidade Federal do Rio Grande do Sul, Caixa Postal 15053, 91501 Porto Alegre, RS, Brasil

ABSTRACT

An original form of utilization of the Similarity Coefficient of Jaccard is proposed using electrophoretic data obtained from different tissues and different developmental stages of the cleistogamous plant Relbunium hypocarpium. This approach allows us to estimate the effect of gene regulation on the variability observed among strains, that is, the degree in which the differences observed are due to differences in ontogenetic regulation (temporal regulation) and tissue differentiation (spatial regulation). This possibility of quantifying the effect of regulatory genes on the variability could also be applied to evolutionary studies.

Keywords: Similarity coefficient; Jaccard; Gene regulation.

REFERENCES

Cavalli-Molina, S., Motta, V.E.P., Schiengold, M. and Winge, H. (1989). Identical isoenzyme patterns in sib plants of Relbunium hypocarpium (Rubiaceae). Rev. Brasil. Genet. 12: 361-368.

Korochkin, L.I. (1981). Gene Interactions in Development. Springer-Verlag, Berlin.

Schiengold, M. (1985). Efeito da regulação gênica na variabilidade isoesterásica de Relbunium hypocarpium (Rubiaceae). Master Thesis. Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil.

Sneath, P.H.A. and R.R Sokal (1973). Numerical Taxonomy. W.H. Freeman, San Francisco, 573 pp.