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Constitutional Y/15 translocation in a woman with lung cancer

A.C. Fett-Conte^I; E.H. Tajara^I; M. Varella-Garcia^I; R.C.S. Santos^II

^IDepartamento de Biologia, Instituto de Biociências, Letras e Ciências Exatas, UNESP, 15055 São José do Rio Preto, SP, Brasil. Send correspondence to E.H.T.
^IIInstituto Butantã, Caixa Postal 65, 05503 São Paulo (RCSS), SP, Brasil

ABSTRACT

In the course of fragile site investigations on 16 patients with leukemia, lymphoma and lung cancer, a 74-year-old woman with lung cancer was found to have additional heterochromatic material on 15p. G, C, Q and Ag-NOR banding suggested that an important part of the long arm of the Y chromosome was translocated to the short arm of chromosome 15.

Keywords: Y/15 translocation; Lung cancer.

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