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Transabdominal chorionic villus sampling: experience with 70 cases

Thomaz Rafael Gollop; Patricia de Campos Pieri; Nadyr Fernandes Naccache; Eloisa Auler-Bittencourt; Alberto Eigier; Decio Hauschild

Serviço de Genética Humana da Associação Maternidade de São Paulo, Rua Félix de Souza, 285, Campo Belo. 04612 São Paulo, SP, Brasil

ABSTRACT

The first 70 cases of Transabdominal Chorionic Villus Sampling (TA-CVS) performed at the Serviço de Genética Humana da Associação Maternidade de São Paulo are reported. All the samples collected between November/87 and February/89 were adequate for analysis and the average number of needle insertions was 1.6. Eighty percent of the tests were done due to advanced maternal age (? 35 years). Six cases (8.6 per cent) of chromosomal abnormalities were detected and the pregnancies terminated. The risk of pregnancy loss in the two week period after the procedure was 1.4 per cent. TA-CVS is an alternative method for prenatal diagnosis with no limitations of gestational age, but further investigation with respect to its safeness is needed.

Keywords: Transabdominal chorionic villus.

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