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Placental phosphoglucomutase polymorphism in Porto Alegre; Brazil

K. Kvitko; T.A. Weimer

Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Caixa Postal 1953, 90001 Porto Alegre, RS, Brasil. Send correspondence to T.A.W.

ABSTRACT

Placental phosphoglucomutase 1PGM1, PGM2 and PGM3 loci) ..was' investigated in a sample of 442 newborns (54% Whites and 46% Blacks) from Porto Alegre, Rio Grande do Sul, Brazil. The gene frequencies found were: Whites:PGMI *2 = 0.24;PGM2*1 = 1.00;PGM3*2 = 0.32; Blacks: PGM1 *2 = 0.22; PGM2*1 = 1.00 and PGM3*2 = 0.45. A heterozygous individual for a possible null allele at the PGM1 locus was found among the Blacks. No significant relationships were found in the joint di_istributions of PGMI- and PGM3, nor was any association detected be- tween PGMI or PGM3 distributions and fetal or placental development.

Keywords: placental; phosphoglucomutase; polymorphism; Brazil.

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