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Distribution of the lewis and secretor traits in Rio de Janeiro, Brazil
Marcos PalatnikI, II; Naci S.M. LaranjeiraI; Maria L.M.S. SimõesI; Juciara B. LoureiroI
ILaboratório de Pesquisa, Serviço de Hemoterapia, Hospital Universitário Clementino Fraga Filho, 3o andar, Universidade Federal do Rio de Janeiro, Avenida Brig. Trompowski, s/n, Ilha do Fun-dio, 21941 Rio de Janeiro, RJ, Brasil. Send correspondence to M.P.
IIDepartamento de Clínica Médica, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil
ABSTRACT
Lewis/Secretor phenotypes and gene frequencies were determined among urban Caucasoids and Blacks of Rio de Janeiro, Brazil. The Black pattern of high prevalence of the Le(a-b-) type was observed in both skin color groups. Both samples fit the equilibrium estimated for two independent loci, and there are no significant differences between their gene frequencies.
Keywords: lewis; secretor.
REFERENCES
Ceppellini, R., Dunn, L.C. and Innella, F. (1959). Immunogenetica. II. Analisi genetica formale dei caratteri Lewis com particolare riguardo alla natura epistatica della specificità Leb. Folia Hered. Pathol. 8: 261-296.
François, A., Sansonetti, N., Mollicone, R., Le Pendu, J., Galton, J., Jaulmes, B. and Oriol, R. (1986). Heterogeneity of Lewis antibodies. A comparison of the reaction of human and animal reagents with synthetic oligosaccharides. Vox. Sang. 50: 227-234.
Guinsburg Saldanha, S. (1982). ABO blood groups and salivary secretion of ABH substances among three racial groups in São Paulo city. Brazil. J. Genet. 5: 175-186.
Palatnik, M., de Sa e Benevides, M.J.F. and Salzano, F.M. (1969). ABH salivary secretion and White/Negro gene flow in a Brazilian population. Hum. Biol. 41: 83-96.
Pittiglio, D.H. (1986). Genetics and biochemistry of A, B, H and Lewis antigens. In: Blood Group Systems: ABH and Lewis (Wallace, M.E. and Gibbs, F.L., eds.). American Association of Blood Banks, Arlington, VA, pp. 1-56.
Salmon, Ch., Cartron, J-P. and Rouger, P. (1984). The Human Blood Groups. Masson Publishing USA, Inc., New York, p. 172.
Sturgeon, Ph. and Arcilla, M.B. (1970). Studies on the secretion of blood group subst ances. I. Observations on the red cell phenotype Le (a+b+x+). Vox Sang. 18: 301-322.